Release: 10-Jul-2007
Title: Solution structure of the Bright/ARID domain from the human JARID1C protein.
PDB index: 2JRZ
Primary Citation: Koehler, C.,  Bishop, S.,  Dowler, E.F.,  Diehl, A.,  Schmieder, P.,  Leidert, M.,  Oschkinat, H.,  Ball, L.J. Backbone and Sidechain 1H, 13C and 15N Resonance Assignments of the Bright/ARID Domain from the Human JARID1C. Protein To be Published
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release: 05-Jun-2007
Title: Reduced form of ADAP hSH3-N-domain
PDB index: 2GTJ
Primary Citation: Zimmermann, J.,  Kuhne, R.,  Sylvester, M.,  Freund, C. Redox-Regulated Conformational Changes in an SH3 Domain. Biochemistry v46 pp. 6971-6977, 2007
Method: NMR, 20 STRUCTURES
Source: Homo sapiens
Remarks: Related PDB Entry: 2GTO (Oxidized form of the domain)

Release: 05-Jun-2007
Title: Oxidized form of ADAP hSH3-N
PDB index: 2GTO
Primary Citation: Zimmermann, J.,  Kuhne, R.,  Sylvester, M.,  Freund, C. Redox-Regulated Conformational Changes in an SH3 Domain. Biochemistry v46 pp. 6971-6977, 2007
Method:NMR, 20 STRUCTURES
Source: Homo sapiens
Remarks: Related PDB Entry: 2GTJ (Reduced form of the domain)

Release: 15-May-2007
Title: Crystal structure of alpha spectrin SH3 domain measured at room temperature
PDB index: 2NUZ
Primary Citation:  Agarwal, V.,  Faelber, K.,  Hologne, M.,  Chevelkov, V.,  Oschkinat, H.,  Diehl, A.,  Reif, B. Comparison of MAS solid-state NMR and X-ray crystallographic data in the analysis of protein dynamics in the solid state. To be Published
Method: X-RAY DIFFRACTION 1.85Å
Source: Gallus gallus
Remarks: 1U06 is the same construct/protein, structure determined from crystals measured at 100K

Release: 15-May-2007
Title: Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)
PDB index: 2JP2
Primary Citation:  Zimmermann, J.,  Jarchau, T.,  Walter, U.,  Oschkinat, H.,  Ball, L.J. 1H, 13C and 15N resonance assignment of the human Spred2 EVH1 domain. J. Biomol. NMR v29 pp. 435-436, 2004
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release: 01-May-2007
Title: The solution structure of the core of mesoderm development (MESD).
PDB index: 2I9S
Primary Citation: Kohler, C.,  Andersen, O.M.,  Diehl, A.,  Krause, G.,  Schmieder, P.,  Oschkinat, H. The solution structure of the core of mesoderm development (MESD), a chaperone for members of the LDLR-family. J Struct Funct Genomics v7 pp. 131-138, 2006
Method: NMR, 20 STRUCTURES
Source: Mus musculus

Release Date: 27-Feb-2007
Title: Solution structure of the RGS domain of human RGS14
PDB index: 2JNU
Primary Citation: Dowler, E.F.,  Diehl, A.,  Schmieder, P.,  Brockmann, C.,  Elkins, J.,  Soundararajan, M.,  Oschkinat, H.,  Ball, L.J. Solution structure of the RGS domain of human RGS14. To be Published
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release Date: 27-Feb-2006
Title: Solution structure of the RGS domain from human RGS18
Primary Citation: Higman, V.A.,  Leidert, M.,  Bray, J.,  Elkins, J.,  Soundararajan, M.,  Doyle, D.,  Gileadi, C.,  Phillips, C.,  Schoch, G.,  Yang, X.,  Brockmann, C.,  Schmieder, P.,  Diehl, A.,  Sundstrom, M.,  Arrowsmith, C.,  Weigelt, J.,  Edwards, A.,  Oschkinat, H.,  Ball, L.J. Solution Structure of the Rgs Domain from Human Rgs18 (Casp Target). To be Published
PDB index: 2OWI
Source: Homo sapiens
Remarks: Structure calculated from the same restraints as in 2JM5, but using a different refinement protocol

Release:  14-Nov-2006
Title: General structural motifs of amyloid protofilaments
PDB index: 2NNT
Primary Citation: Ferguson, N.,  Becker, J.,  Tidow, H.,  Tremmel, S.,  Sharpe, T.D.,  Krause, G.,  Flinders, J.,  Petrovich, M.,  Berriman, J.,  Oschkinat, H.,  Fersht, A.R. General structural motifs of amyloid protofilaments. Proc.Natl.Acad.Sci.Usa v103 pp. 16248-16253, 2006
Method: NMR, 10 STRUCTURES
Source: Homo sapiens

Release: 31-Okt-2006
Title: Solution structure of RGS10
PDB index: 2I59
Primary Citation:  Fedorov, O.,  Higman, V.,  Diehl, A.,  Soundarajan, M.,  Lemak, A.,  Elkins, J.,  Oschkinat, H.,  Ball, L.J. Solution structure of human regulator of G-protein signaling 10. To be Published
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release Date: 24-Okt-2006
Title: Solution Structure of the RGS domain from human RGS18
PDB index: 2JM5 (2OWI, refined structure)
Primary Citation: Higman, V.A.,  Leidert, M.,  Bray, J.,  Elkins, J.,  Soundararajan, M., Doyle, D.,  Gileadi, C.,  Phillips, C.,  Schoch, G.,  Yang, X.,  Brockmann, C.,  Schmieder, P.,  Diehl, A.,  Sundstrom, M.,  Arrowsmith, C.,  Weigelt, J.,  Edwards, A.,  Oschkinat, H., Ball, L.J., to be published
Method: NMR, 20 STRUCTURES
Source: Homo sapiens
Remarks: Structure solved in collaboration with the Structural Genomics Consortium, Oxford

Release: 17-Okt-2006
Title: Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain
PDB index: 2EXG
Primary Citation:  Joshi, M.,  Vargas, C.,  Boisguerin, P.,  Diehl, A.,  Krause, G.,  Schmieder, P.,  Moelling, K.,  Hagen, V.,  Schade, M.,  Oschkinat, H. Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl. v45 pp. 3790-3795, 2006
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release: 04-Apr-2006
Title: Solution structure of the Trypanosoma cruzi cysteine protease inhibitor chagasin
PDB index: 2FO8
Primary Citation:  Salmon, D.,  do Aido-Machado, R.,  Diehl, A.,  Leidert, M.,  Schmetzer, O.,  de Lima, A.A.P.,  Scharfstein, J.,  Oschkinat, H.,  Pires, J.R. Solution Structure and Backbone Dynamics of the Trypanosoma cruzi Cysteine Protease Inhibitor Chagasin.  J.Mol.Biol. v357 pp. 1511-1521, 2006
Method: NMR, 15 STRUCTURES
Source: Trypanosoma cruzi
Remarks: Related PDB Entry - 2C34 (Leishmania mexicana ICP)

Release: 15-Nov-2005
Title: Structure of AF-6 PDZ domain
PDB index: 1XZ9
Primary Citation:  Joshi, M.,  Boisguerin, P.,  Leitner, D.,  Volkmer-Engert, R.,  Moelling, K.,  Schade, M.,  Schmieder, P.,  Krause, G.,  Oschkinat, H. Structure of AF-6 PDZ domain. To be Published
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release: 15-Mar-2005
Title: Structure of the antimicrobial hexapeptide cyc-(RRNalNalRF) bound to DPC micelles
PDB index: 1SKL
Primary Citation: Appelt, C.,  Soderhall, J.A.,  Bienert, M.,  Dathe, M.,  Schmieder, P. Structures of antimicrobial hexapeptides bound to DPC micelles. To be Published
Method: NMR, 10 STRUCTURES
Source: Synthetic construct

Release: 12-Apr-2005
Title: Structure of the FBP11WW1 domain
PDB index: 1YWJ
Primary citation: Pires, J.R.,  Parthier, C.,  Aido-Machado, R.,  Wiedemann, U.,  Otte, L.,  Bohm, G.,  Rudolph, R.,  Oschkinat, H.   Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain.  J.Mol.Biol.   v348 pp. 399-408, 2005  
Method: NMR, 15 STRUCTURES
Source: Homo sapiens
Remarks: 1YWI FBP11WW1 domain complexed to the peptide APPTPPPLPP

Release: 15-Mar-2005
Title: Structure of the antimicrobial hexapeptide cyc-(KKWWKF) bound to DPC micelles
PDB index: 1SKK
Primary Citation:  Appelt, C.,  Soderhall, J.A.,  Bienert, M.,  Dathe, M.,  Schmieder, P. Structures of antimicrobial hexapeptides bound to DPC micelles. To be Published
Method: NMR, 10 STRUCTURES
Source: Synthetic construct

Release: 12-Apr-2005
Title: Structure of the FBP11WW1 domain complexed to the peptide APPTPPPLPP
PDB index: 1YWI
Primary Citation:  Pires, J.R.,  Parthier, C.,  Aido-Machado, R.,  Wiedemann, U.,  Otte, L.,  Bohm, G.,  Rudolph, R.,  Oschkinat, H. Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain. J.Mol.Biol. v348 pp. 399-408, 2005
Method: NMR, 15 STRUCTURES
Source: Homo sapiens
Remarks: 1YWJ FBP11WW1 domain without ligand

Release: 15-Mar-2005
Title: Structure of the antimicrobial hexapeptide cyc-(RRYYRF) bound to DPC micelles
PDB index: 1SKI
Primary Citation: Appelt, C.,  Soderhall, J.A.,  Bienert, M.,  Dathe, M.,  Schmieder, P. Structures of antimicrobial hexapeptides bound to DPC micelles. To be Published
Method: NMR, 10 STRUCTURES
Source: Synthetic construct

Release:  12-Apr-2005
Title: Solution structure of exoenzyme S
PDB index: 1R4T
Primary Citation:  Langdon, G.M.,  Leitner, D.,  Labudde, D.,  Kuhne, R.,  Schmieder, P.,  Aktories, K.,  Oschkinat, H.O.,  Schmidt, G. Solution structure of the N-terminal GTPase activating domain of Pseudomonas aeruginosa exoenzyme S. To be Published
Method: NMR, 23 STRUCTURES
Source: Pseudomonas aeruginosa

Release: 25-Jan-2005
Title: NMR Solution Structure of Subunit B8 from Human NADH-Ubiquinone Oxidoreductase Complex I (CI-B8)
PDB index: 1S3A
Primary Citation:  Brockmann, C.,  Diehl, A.,  Rehbein, K.,  Strauss, H.,  Schmieder, P.,  Korn, B.,  Kuhne, R.,  Oschkinat, H. The oxidized subunit B8 from human complex I adopts a thioredoxin fold. Structure v12 pp. 1645-1654, 2004
Method: NMR, 19 STRUCTURES
Source: Homo sapiens

Release: 13-Jan-2005
Title: Crystal structure of chicken alpha-spectrin SH3 domain
Primary Citation:  Chevelkov, V.,  Faelber, K.,  Diehl, A.,  Heinemann, U.,  Oschkinat, H.,  Reif, B. Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR. J.Biomol.Nmr v31 pp. 295-310, 2005
PDB index: 1U06
Method: X-RAY DIFFRACTION 1.49Å
Source: Gallus gallus

Release  09-Nov-2004
Title: Solution structure of SEP domain from human p47
PDB index: 1SS6
Primary Citation:  Soukenik, M.,  Diehl, A.,  Leidert, M.,  Sievert, V.,  Buessow, K.,  Leitner, D.,  Labudde, D.,  Ball, L.J.,  Lechner, A.,  Nagler, D.K.,  Oschkinat, H. The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L. FEBS Lett. v576 pp. 358-362, 2004
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release: 28-Sep-2004
Title: Structure of the antimicrobial hexapeptide cyc-(RRWWRF) bound to DPC micelles
PDB index: 1QVK
Primary Citation: Appelt, C.,  Wessolowski, A.,  Soderhall, J.A.,  Dathe, M.,  Schmieder, P. Structure of the Antimicrobial, Cationic Hexapeptide Cyclo(RRWWRF) and Its Analogues in Solution and Bound to Detergent Micelles Chembiochem v6 pp. 1654-1662, 2005
Method: NMR, 10 STRUCTURES
Source: Synthetic construct

Release: 28-Sep-2004
Title: Structure of the antimicrobial hexapeptide cyc-(RRWWRF) bound to SDS micelles
PDB index: 1QVL
Primary Citation: Appelt, C.,  Wessolowski, A.,  Soderhall, J.A.,  Dathe, M.,  Schmieder, P. Structure of the Antimicrobial, Cationic Hexapeptide Cyclo(RRWWRF) and Its Analogues in Solution and Bound to Detergent Micelles Chembiochem v6 pp. 1654-1662, 2005
Method: NMR, 10 STRUCTURES
Source: Synthetic construct

Release:  06-Jul-2004
Title: NMR structure of human Cofilin
PDB index: 1Q8G
Primary Citation:  Pope, B.J.,  Zierler-Gould, K.M.,  Kuhne, R.,  Weeds, A.G.,  Ball, L.J. The solution structure of human cofilin: rationalizing actin binding and pH sensitivity J.Biol.Chem. v279 pp. 4840-4848, 2004
Method: NMR, 20 STRUCTURES
Source: Homo sapiens
Remarks: Related PDB Entry: 1Q8X (NMR structure of human cofilin)

Release: 20-Apr-2004
Title: Structure of a helically extended SH3 domain of the T cell adapter protein ADAP
PDB index: 1RI9
Primary Citation:  Heuer, K.,  Kofler, M.,  Langdon, G.,  Thiemke, K.,  Freund, C. Structure of a Helically Extended SH3 Domain of the T Cell Adapter Protein ADAP. STRUCTURE v12 pp. 603-610, 2004
Method: NMR, 20 STRUCTURES
Source: Homo sapiens

Release:  05-Jan-2000
Title: GYF DOMAIN FROM HUMAN CD2BP2 PROTEIN
PDB index: 1GYF
Primary Citation:  Freund, C.,  Dotsch, V.,  Nishizawa, K.,  Reinherz, E.L.,  Wagner, G. The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences. Nat.Struct.Biol. v6 pp. 656-660, 1999
Method: NMR, 16 STRUCTURES
Source: Homo sapiens

Release:  15-June-2004
Title: Solution structure of the BRCT-c domain from human BRCA1
PDB index: 1OQA
Primary Citation:  Gaiser, O.J.,  Ball, L.J.,  Schmieder, P.,  Leitner, D.,  Strauss, H.,  Wahl, M.,  Kuhne, R.,  Oschkinat, H.,  Heinemann, U. Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1. Biochemistry v43 pp. 15983-15995, 2004
Method:  NMR, 15 STRUCTURES
Source: Homo sapiens

Release: 06-Jul-2004
Title: NMR structure of human cofilin
PDB index: 1Q8X
Primary Citation: Pope, B.J.,  Zierler-Gould, K.M.,  Kuhne, R.,  Weeds, A.G.,  Ball, L.J. The solution structure of human cofilin: rationalizing actin binding and pH sensitivity J.Biol.Chem. v279 pp. 4840-4848, 2004
Method: NMR, 20 STRUCTURES
Source: Homo sapiens
Remarks: Related PDB Entry: 1Q8G (NMR structure of human cofilin)

Release: 09-Mar-2004
Title: Solution structure of the Z-DNA binding domain of the vaccinia virus gene E3L
PDB index: 1OYI
Primary Citation: Kahmann, J.D.,  Wecking, D.A.,  Putter, V.,  Lowenhaupt, K.,  Kim, Y.-G.,  Schmieder, P.,  Oschkinat, H.,  Rich, A.,  Schade, M. The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro. Proc.Natl.Acad.Sci.USA v101 pp. 2712-2717, 2004
Method: NMR, 20 STRUCTURES
Source: Vaccinia virus

Release Date: 20-Nov-2002
Titel: Solid-State Mas NMR Structure Of The A-Spectrin SH3 Domain
PDB index: 1M8M
Primary Citation: Castellani, F., Van Rossum, B., Diehl, A., Schubert, M., Rehbein, K., Oschkinat, H. Structure of a Protein Determined by Solid-State Magic-Angle-Spinning NMR Spectroscopy. Nature 420 pp. 98 (2002)
Source: Gallus gallus
Remarks: First structure solved with solid state NMR

Release Date: Okt. 2004
Titel: NMR solution structure of the human p47 SEP domain
PDB index: 1SS6
Primary Citation: Michael Soukenik, Anne Diehl, Martina Leidert, Volker Sievert, Konrad Büssow, Dietmar, Leitner, Dirk Labudde, Linda J. Ball, Annette Lechner, Dorit K. Nägler, and Hartmut Oschkinat. The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L. FEBS Lett. 2004 Oct 22;576(3):358-362
Source: Homo sapiens
Remarks: novel fold

Release Date: Sep. 2004
Titel: NMR Solution Structure of Subunit B8 from Human NADH-Ubiquinone Oxidoreductase Complex I (CI-B8)
PDB index: 1S3A
Primary Citation: Brockmann, C., Diehl, A., Rehbein, K., Kuhne, R., Oschkinat, H.
The oxidized subunit b8 from human complex I adopts a thioredoxin fold
Structure (Camb). 2004 Sep;12(9):1645-54
Source: Homo sapiens

Release Date: 01-Jul-2003
Titel: C-Terminal Opca Domain Of Ycdc24P
PDB index: 1PQS
Primary Citation: Leitner, D., Wahl, M., Labudde, D., Diehl, A., Schmieder, P., Pires, J. R., Fossi, M., Leidert, M., Krause, G., Oschkinat, H.:
Solution Structure of the C-Terminal Opca Domain of Ycdc24P
FEBS Lett. 2005 Jul 4;579(17):3534-8
Source: Saccharomyces cerevisiae

Release Date:  30-Dec-1998
Titel:  Syntrophin PDZ Domain
PDB index: 2PDZ
Primary Citation:
Schultz, J., Hoffmuller, U., Krause, G., Ashurst, J., Macias, M. J., Schmieder, P., Schneider-Mergener, J., Oschkinat, H.:
Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels
Nat Struct Biol 5 pp. 19  (1998)
Source: Mus musculus
Remarks: red: ligand

Release Date: 07-Nov-2001
Titel: DHBPS of Riboflavin Biosynthesis
PDB index: 1IEZ
Primary Citation: Kelly, M. J. S., Ball, L. J., Krieger, C., Yu, Y., Fischer, M., Schiffmann, S., Schmieder, P., Kuhne, R., Bermel, W., Bacher,  A.,Richter, G., Oschkinat, H. The NMR Structure of the 47-kDa Dimeric Enzyme 3,4- Dihydroxy-2- Butanone-4- Phosphate Synthase and Ligand Binding Studies Reveal the  Location of the Active Site. Proc.Nat.Acad.Sci.USA 98 pp. 13025 (2001)
Source: Escherichia coli

Release Date:  20-Sep-2000
Titel:  Domain Of Human Vasodilator-Stimulated Phosphoprotein (Vasp), EVH1
PDB index: 1EGX
Primary Citation: Kelly, M. J. S., Ball, L. J., Krieger, C., Yu, Y., Fischer, M., Schiffmann, S., Schmieder, P., Kuhne, R., Bermel, W., Bacher,  A.,Richter, G., Oschkinat, H. The NMR Structure of the 47-kDa Dimeric Enzyme 3,4- Dihydroxy-2- Butanone-4- Phosphate Synthase and Ligand Binding Studies Reveal the  Location of the Active Site. Proc.Nat.Acad.Sci.USA 98 pp. 13025 (2001)
Source: Escherichia coli

Release Date:  19-Mar-1999
Titel:  Ra-Domain Of Ral Guanosine-Nucleotide Dissociation Stimulator; RALgds
PDB index: 1RAX
Primary Citation: Mueller, T. D., Handel, L., Schmieder, P., Oschkinat, H. High-Resolution Structure of the Ra-Domain of Human Ralgds and a Dynamics Study of its Binding Loop to Ras. to be published
Source: Homo sapiens

Release Date:  06-Oct-1999
Titel:  SAM Domain From The Receptor Tyrosine Kinase Ephb2
PDB index: 1SGG
Primary Citation: Smalla, M., Schmieder, P., Kelly, M., Ter Laak, A., Krause, G., Ball, L., Wahl, M., Bork, P., Oschkinat, H. Solution Structure of  the Receptor Tyrosine Kinase Ephb2 Sam Domain andIIdentification of Two Distinct Homotypic Interaction Sites. Protein Sci. 8 pp. 1954 (1999)
Source: Gallus gallus

Release Date:  on hold
Titel:  Spred2 EVH1
PDB index: 1Q8E
Primary Citation: Structure of the murine Spred2 EVH1 domain (Q924S7). This domain is the first example for a new class of EVH1 domains, most likely binding to a different type  of ligand than the two classes kown so far (e.g. VASP and Homer proteins). To  date, seven Spred proteins have been identified in the databases. Juergen Zimmermann

Release Date:  2005-04-12
Titel:  Exoenzyme S
PDB index: 1R4T
Primary Citation: Langdon G.M. , Schmidt G., Leitner D., Schmieder P., Aktories K., Solution structure of the N-terminal GTPase activating domain of Pseudomonas aeruginosa exoenzyme S. 2003, to be published

Release Date:  04-Mar-2003
Titel:  Scpex13P Sh3 Domain
PDB index: 1NM7
Primary Citation: Pires, J. R., Hong, X., Brockmann, C., Volkmer-Engert, R., Schneider-Mergener, J., Oschkinat, H., Erdmann, R. The Scpex13P SH3 Domain Exposes Two Distinct Binding Sites for Pex5P and Pex14P. J.Mol.Biol. 326 pp. 1427 (2003)
Source: Saccharomyces cerevisiae

Release Date:  19-Oct-1999
Titel:  Z- Domain Of Adar1
PDB index: 1QGP
Primary Citation: Schade, M., Turner, C. J., Kuehne, R., Schmieder, P., Lowenhaupt, K., Herbert, A., Rich, A., Oschkinat, H. Solution Structure of Z_Alpha Domain of the Human Mrna Editing Enzyme Adar1 Reveals a Prepositioned Binding Surface for Z-DNA Proc.Nat.Acad.Sci.USA 96 pp. 12465 (1999)
Source: Homo sapiens

Release Date:  07-Aug-2002
Titel:  Sodd Bag Domain
PDB index: 1M7K
Primary Citation: Brockmann, C., Leitner, D., Labudde, D., Diehl, A., Sievert, V., Büssow, K., Kühne, R., and Oschkinat, H. The solution structure of the SODD BAG-domain and a model of the SODD-BAG/HAP70 complex reveal additional SODD subfamily-specific electrostatic interactions. FEBS Lett. 2004 Jan 30;558(1-3):101-6
Source: Homo sapiens

Titel:  BR retinal
Primary Citation: Patzelt H, Simon B, AntoniusterL, Kessler B, Kühne R, Schmieder P, Oesterhelt D, Oschkinat H. The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9765-70
Source: Halobacterium Salinarium

Release Date:  28-Dec-2001
Titel:  Yap65 WW Domain Complexed To N-(N-Octyl)-Gpppy-Nh2
PDB index: 1K9Q
Primary Citation: Pires, J. R., Taha-Nejad, F., Toepert, F., Ast, T., Hoffmuller, U., Schneider-Mergener, J., Kuhne, R., Macias, M. J., Oschkinat, H. Solution Structures of the Yap65 Ww Domain and the Variant L30 K in Complex with the Peptides Gtppppytvg, N-(N-Octyl)-Gpppy and Plppy and the Application of Peptide Libraries Reveal a Minimal Binding Epitope. J.Mol.Biol. 314 pp. 1147 (2001)
Remarks: blue: binding site, yellow: ligand

Release Date:  20-Apr-2000
Titel:  WW prototype
PDB index: 1E0M
Primary Citation: Macias, M. J., Gervais, V., Civera, C., Oschkinat, H. Structural Analysis of WW Domains and Design of a WW Prototype Nat.Struct.Biol. 7 pp. 375 (2000)
Source: Gallus gallus
Remarks: blue: binding site

Release: 20-Nov-2002
Title: CD2BP2-GYF domain in complex with proline-rich CD2 tail segment peptide
PDB index: 1L2Z
Primary Citation:  Freund, C.,  Kuhne, R.,  Yang, H.,  Park, S.,  Reinherz, E.L.,  Wagner, G. Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules Embo J. v21 pp. 5985-5995, 2002
Method: NMR, 15 STRUCTURES
Source: Homo sapiens
Remarks: Related PDB Entry: 1GYF

Release Date:  28-Dec-2001
Titel:  Yap65 (L30K Mutant) WW Domain in complex With Gtppppytvg Peptide
PDB index: 1JMQ
Primary Citation: Smalla, M., Schmieder, P., Kelly, M., Ter Laak, A., Krause, G., Ball, L., Wahl, M., Bork, P., Oschkinat, H. Solution Structure of  the Receptor Tyrosine Kinase Ephb2 Sam Domain andIIdentification of Two Distinct Homotypic Interaction Sites. Protein Sci. 8 pp. 1954 (1999)
Source: Gallus gallus

Release Date:  28-Dec-2001
Titel:  Yap65 WW Domain complexed to Acetyl-Plppy
PDB index: 1K9R
Primary Citation: Pires, J. R., Taha-Nejad, F., Toepert, F., Ast, T., Hoffmuller, U.,Schneider-Mergener, J., Kuhne, R., Macias, M. J., Oschkinat, H. Solution Structures of the Yap65 WW Domain and theVariant L30 K in Complex with the Peptides Gtppppytvg,N-(N-Octyl)-Gpppy and Plppy and the Application of PeptideLibraries Reveal a Minimal Binding Epitope. J.Mol.Biol. 314 pp. 1147 (2001)
Remarks: blue: binding site, yellow: ligand

Release Date:  02-Nov-2001
Titel:  Yap65 WW Domain, S24-Amino-Ethylsulfanyl-Acetic Acid Mutant
PDB index: 1K5R
Primary Citation: Ferguson, N., Pires, J. R., Toepert, F., Johnson, C. M., Pan, Y. P., Volkmer-Engert, R., Schneider-Mergener, J., Daggett, V.,Oschkinat, H., Fersht, A. R. Using Flexible Loop Mimetics to extend Phi-Value Analysis to Secondary Structure Interactions. Proc.Nat.Acad.Sci.USA 98 pp. 13008 (2001)
Remarks: blue: binding site, yellow: ligand

Release Date:  02-Jun-2000
Titel:  Yjq8WW Domain
PDB index: 1E0N
Primary Citation: Macias, M. J., Gervais, V., Civera, C., Oschkinat, H. Structural Analysis of Ww Domains and Design of a WW Prototype. Nat.Struct.Biol. 7 pp. 375 (2000)
Source: Saccharomyces cerevisiae
Remarks: blue: binding site

Release Date:  20-Apr-2000
Titel:  Fbp28 WW Domain
PDB index: 1EOL
Primary Citation: Macias, M. J., Gervais, V., Civera, C., Oschkinat, H. Structural Analysis of WW Domains and Design of a WW Prototype. Nat.Struct.Biol. 7 pp. 375 (2000)
Source: Mus musculus
Remarks: blue: binding site